Unilateral fetal VM was thought to be quite unusual in the older sonography literature,14 but it must be remembered that in many cases, only the trigone furthest from the sonography probe is measured or measured with certainty, because of the problems of near-field effects.9 This was reflected in a recent sonography and iuMR imaging study in which unilateral VM was shown in 51/85 cases (60%) of fetuses with mild VM.15 There has been debate in the literature about the significance of unilateral isolated VM in the fetus in relation to bilateral VM. However, measuring the ventricles is a standard part of the prenatal ultrasound screening done in the second trimester. Careers. Ventriculomegaly is often diagnosed through prenatal ultrasound when the brain ventricles are measured. In the 2024 weeks' group, there was a mean absolute difference of <1 mm between the 2 observers in each case. Every pregnant woman in Wales is offered a fetal anomaly scan when they are between 18 and 20 weeks pregnant. These tests may include: During pregnancy, the only treatment is to monitor the condition of the fetus and whether the ventricles get bigger. I really don't want my friends to worry until we know what to worry about. *, full or bulging soft spot at the top of the head, abnormal eye movement, such as not looking upward or always looking downward, An injury or problem with brain development around the ventricles, A blockage or imbalance in the ventricular system which prevents spinal fluid from moving or being absorbed normally. We'll help you find the best provider for your child. Your child will not have to stay in the hospital as the shunt lives under the skin. We can compare our findings with those of Parilla et al by combining the data in Figs 2B and C. With this combination, our group of isolated VM cases with trigones between 10 and 15 mm showed stabilization in 27/36 (75%), normalization in 5/36 (14%), and progression in 4/36 (11%). Normalization was more commonly seen in the 1012 mm group (25/47) compared with the 1315 mm group (1/16), whereas progression was more equally distributed (7/47 and 3/16). 94158-2549, 1-800-RX-FETUS Our researchers are currently investigating whether the results of a fetal MRI can indicate the likelihood of disability and what families may expect for their child's health and development. Stress-free visits From open fetal surgery to minimally invasive techniques, The first fetal surgery in the world was performed at UCSF over 3 decades ago, With fetal MRI we can detect abnormalities in the fetal brain that are not visible on prenatal ultrasound, Better fetal diagnosis and treatment through next-generation gene sequencing. The iuMR imagings were all reported clinically at the time of the examination, but for the purposes of this study, all were reviewed by radiologists experienced in iuMR imaging brain studies (P.D.G., M.J.R.) 8600 Rockville Pike Epub 2019 Jul 11. Epub 2017 May 16. The severity of ventriculomegaly depends on how enlarged the brain is. This fluid buildup usually happens slowly, over the course of weeks. The most common effect in the child is developmental delay. Those conclusions should be predicated by the technical issues described above and by the low numbers from the pooled studies (approximately 100 cases). Bookshelf However, not all women have it. Melchiorre et al9 analyzed 5 published studies and came to the conclusion that there were no statistically significant differences in outcome in terms of neurodevelopmental delay (6% in unilateral VM and 7.4% in bilateral VM). Technology & Innovation Development Office, endoscopic third ventriculostomy/choroid plexus cauterization, trouble looking up when the head is facing forward, a problem that prevents cerebrospinal fluid (CSF) fluid from circulating and being absorbed normally in the brain, which causes, a minor imbalance in fluid circulation and absorption. Access ANCHOR, the intranet for Nationwide Childrens employees. Expertise. If the ventriculomegaly progresses, the baby may have symptoms of hydrocephalus, including: Although theres not always a single reason why a child develops ventriculomegaly, there are four main factors that can cause enlargement of the ventricles: Ventriculomegaly usually occurs spontaneously, which means that a child does not inherit the condition from the parents. San Francisco Infections are more frequently found in cases of severe ventriculomegaly which develop in late pregnancy. Our specialists handle conditions ranging from the common to the most rare. Her pregnancy to date had been uncomplicated without notable fevers, illnesses, or need for medications aside from prenatal vitamins. When you are pregnant you will have an ultrasound. I have been referred to another hospital for an MRI and am so terrified that they will tell me it's getting bigger and my baby will be neurologically challenged. Usually the problem is with one or both of the top ventricles. This article has not yet been cited by articles in journals that are participating in Crossref Cited-by Linking. World-class docs Ventriculomegaly is a condition in which the ventricles appear larger than normal on a prenatal ultrasound. In addition, we did not find any further diagnostic information on the 3032 weeks' iuMR imaging examination in the 5 cases shown to have brain abnormalities on the 2024 weeks' iuMR imaging studies. UCSF Benioff Children's Hospitals medical specialists have reviewed this information. In such a situation, a ventriculoperitoneal shunt (VP shunt) may be needed. This seems to be related to the size of the ventricles, whether the ventriculomegaly is isolated and the cause. Here's how to access them. Mom's age is 25. Symptoms of early pregnancy include a missed period, needing to pee more often, tender breasts, feeling tired and morning sickness. Implantation bleeding occurs around the time you would expect to have a menstrual period. Most affected pregnancies have been terminated . Cytomegalovirus Diagnostic points Risk of transmission to the fetus with maternal primary infection is approximately 30% to 40% and 0.15% to 2% with recurrent infection. 1997 Jul-Aug;6(4):241-4. doi: 10.1002/(SICI)1520-6661(199707/08)6:4<241::AID-MFM11>3.0.CO;2-H. Scelsa B, Rustico M, Righini A, Parazzini C, Balestriero MA, Introvini P, Spaccini L, Mastrangelo M, Lista G, Zuccotti GV, Veggiotti P. Eur J Paediatr Neurol. Lymphocytic choriomeningitis virus is a rodent-borne arenavirus that can cause congenital infection affecting the developing central nervous system. Overall 16% of 63 cases showed progression (ie, became severe), 43% stabilized (remained within 10- to 15-mm range), and 41% normalized (became <10 mm). All images were acquired at 1.5T scanner (either Infinion or HDx, GE Healthcare, Milwaukee, Wisconsin). Speak with our Fetal Center team. Ventricles develop early in pregnancy and can be seen on a prenatal ultrasound in the second trimester, at about the 15th week. At 29 weeks, did a prenatal MRI and sono at a children . Nine of 99 women (9%) had fetuses with brain abnormalities other than VM recognized on the first iuMR imaging. The other side of the argument, however, is the important observation that there was no advantage in delaying iuMR imaging until 3032 weeks as suggested in many parts of the published sonography literature.9 This is in contrast to sonography because the meta-analysis performed by Melchiorre et al9 showed a 12.8% extra pickup rate for follow-up sonography compared with the initial study. This information will help parents make decisions during pregnancy and prepare for challenges their child and family may face. CSF is a fluid that protects the brain and spinal cord. I went to my 20 week scan and was told that a ventricle on our babies brain was measuring. Trigone measurements can be made in a highly repeatable fashion on iuMR imaging and should provide a good method to re-investigate the significance of changes in the degree of VM or the presence of unilateral VM in the future. Introduction. was in attendance during the study to confirm that diagnostic-quality images had been obtained. In the remaining 15% of cases, the ventriculomegaly will worsen. None of those diagnoses were changed on the basis of the 3032 weeks' iuMR imaging examination (examples are shown in Figs 3 and 4). Third Trimester Ventriculomegaly. Mommy2Kian Kaden and . Twenty 5-mm-thick sections of the fetal brain were obtained (18- to 25-second acquisitions) in the 3 natural orthogonal planes. This can occur when CSF becomes trapped in the spaces, causing them to grow larger. Bethesda, MD 20894, Web Policies Our staff can talk to you about these test results and inform you what challenges you may expect. Patients with a VP shunt will require regular follow up with neurosurgery to make sure the shunt continues to function properly. Two experienced observers measured the width of the trigones, and the results were compared, to test reliability. These children would be more likely to have neurological disabilities. It is a very safe procedure which can help your child's development as it helps relieve pressure to the brain caused by the buildup of cerebrospinal fluid. A VP shunt is the surgical implantation of a small plastic catheter that drains the cerebrospinal fluid into a part of the body that can easily absorb the fluid such as the abdomen or peritoneum (membrane that forms the lining of the abdominal cavity). Fetus was diagnosed with ventriculomegaly at 22 weeks, can we continue with the pregnancy or should we need to abort. 2021 Dec;27(6):428-436. doi: 10.12809/hkmj208850. In most cases, we know by six months whether your baby needs treatment. Halfway through my pregnancy with Megan, she was diagnosed with fetal ventriculomegaly. In the 2024 weeks' group, 16/40 (40%) fetuses had asymmetric isolated VM. All images are from single-shot fast spin-echo sequences in the coronal plane anteriorly (A and B), the coronal plane posteriorly (C and D), and the sagittal plane (E and F). Fetal ventriculomegaly (VM) refers to the abnormal enlargement of one or more ventricles of the brain in-utero. Because the reproducibility studies showed that the difference of trigone measurements between the 2 observers was never >2 mm, we took a difference of mean trigone size of 3 mm to signify asymmetric VM. When enlargement of the lateral ventricles (10 mm) is identified, a thorough evaluation should . Here to serve you 2017 Jul;33(7):1113-1123. doi: 10.1007/s00381-017-3441-y. Pre-term or Cesarean deliveries are not needed unless there are other fetal or obstetrical problems, such as when the size of the head prevents a vaginal delivery. J Matern Fetal Med. and M.J.R.) The other women were either lost to follow-up or declined the invitation to return. This can be done by placing a ventriculoperitoneal shunt or performing a surgery to reduce spinal fluid and create a hole in the floor of one the ventricles to bypass the blockage. Patient relations reps and nursing supervisors are here to answer questions and address concerns. But it's normal to wonder if you need a test or not. It is usually diagnosed at a routine fetal anomaly scan at 18-22 weeks gestation. We have not shown any advantage in repeating iuMRI at 3032 weeks' gestation in cases of isolated fetal VM over and above the initial iuMR imaging findings at 2024 weeks. Prostate cancer staging takes into account a TNM staging system (primary site, nodal and distant metastases), pretreatment PSA and histological grading. It can be monitored during pregnancy with repeated ultrasounds to look for slowly enlarging ventricles. Role of prenatal magnetic resonance imaging in fetuses with isolated mild or moderate ventriculomegaly in the era of neurosonography: international multicenter study. After the fetal head was located, single-shot fast spin-echo sequences were run by using the following typical parameters: TR, 20,000 ms; TEeff, 75 ms; echo-train length, 132; FOV, 25 cm; matrix size, 248 256; NEX, 1; flip angle, 120. RESULTS: There was excellent reproducibility of trigone measurements between the 2 observers, with a mean absolute difference of <1 mm in the 40 fetuses that were ultimately shown to have isolated VM. Clipboard, Search History, and several other advanced features are temporarily unavailable. The importance of precise and accurate measurements of the trigone relates to the known risk of poor postnatal outcome. The .gov means its official. Fetal ventriculomegaly is a congenital finding that affects the brain. Social workers ease the effect of illness, injury and hospitalization on your family with counseling and assistance to help you navigate the challenges. 2014 Jul;34(5):387-91. doi: 10.3109/01443615.2014.896885. Because of this I was booked in for a level 2 scan at the fetal medicine unit. Ventriculomegaly is the most common fetal brain abnormality, occurring in up to 1.5 per 1,000 pregnancies. Unable to load your collection due to an error, Unable to load your delegates due to an error. This condition means a dilated fluid-filled v. Getting Pregnant; Pregnancy; Birth; Breastfeeding; Baby; Parenting . This is a small, plastic tube that's implanted in the brain and threaded under the skin to the abdomen; it allows the excess CSF to drain into the abdominal cavity, where it can be absorbed by the body. Retrospective review of the 2024 weeks' iuMR imaging study did show the callosal abnormality. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). Accessibility Would you like email updates of new search results? Having a Zika infection during pregnancy can cause devastating damage to the fetus's central nervous system. The entire surface of the brain and spine cord is bathed by a fluid called cerebrospinal fluid (CSF). The two components of the central nervous system are the brain and the spinal cord. . If a prenatal ultrasound shows enlarged ventricles, your doctor may recommend additional tests to determine the cause and check for associated problems. Admission. Cerebrospinal fluid is a clear liquid that surrounds the brain and spinal cord to provide cushioning from jolts. Ultrasound Obstet Gynecol. Because it uses a different technology, fetal MRI can detect other problems in your fetuss brain that cannot be detected on ultrasound. We have looked at changes in ventricular size during the 812 week period between the 2 MR imaging examinations and studied interobserver reproducibility of the trigone measurements on the MR imaging studies. The enlargement may or may not be related to ventricular obstruction and increased intracranial pressure; therefore, the term "hydrocephalus" is not used. If tests show that your baby's cerebrospinal fluid is not draining well and the ventricles are severely enlarged, this may indicate hydrocephalus. We can help you figure it out. Serial ultrasound follow-up would be required to assess its progression with advancing gestation. 2018 Nov;22(6):919-928. doi: 10.1016/j.ejpn.2018.04.001. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). If the lateral ventricles are 10 millimeters or greater in size then you will be told that your fetus has "ventriculomegaly". In only 1 of 41 cases (2%, 95% confidence interval, 0%13%, binomial exact method) assumed to have isolated VM on the 2024 weeks' examination was a further brain abnormality shown on the 3032 weeks' study (hypogenesis of the corpus callosum). The cutoff of normality is <10 mm at any stage of pregnancy, and this is based on 2 large studies that showed a trigone measurement of 10 mm is between 3 and 4 standard deviations above the mean, assuming a normal distribution.1,2 With that classification, approximately 1% of pregnancies are complicated by VM.9 Our earlier article showed good agreement between trigone measurements made by different observers by using sonography and iuMR imaging. Anyone else with a child with ventriculomegaly? Oakland The contents of the brain consist primarily of brain tissue, blood and cerebrospinal fluid (CSF). In these circumstances, we might expect that many of the women who declined follow-up iuMR imaging would have had nonprogressive ventricular measurements and no additional findings on sonography, so our estimate of the rate of progressive VM may well be a little high. In the other 50% of cases, the ventriculomegaly will remain stable. These are called ventricles. Fetal magnetic resonance imaging (MRI) may yield additional information. The rate of infection is 10 e 20 % in severe ventriculomegaly [18, 19] and 1 e 5 % in mild ventriculomegaly [8, 18-20]. Role of prenatal magnetic resonance imaging in fetuses with isolated mild or moderate ventriculomegaly in the era of neurosonography: international multicenter study Either a flexible phased array body coil or a cardiac coil was used, and a series of 3-plane scout views was obtained. Hydrocephalus is a progressive problem so usually the fluid builds up slowly over the course of weeks after your baby is born. Ventriculomegaly develops early in pregnancy. I've read up and this is considered as mild Ventriculomegaly but still abnormal. Two of the main factors that cause enlarged ventricles are: Ventriculomegaly usually occurs spontaneously. Childs Nerv Syst. National Library of Medicine We encourage you to discuss any questions or concerns you may have with your child's provider. Without more specific study, however, this estimate cannot be confirmed, and there are many other complex factors to consider, which probably have a significant influence on any decision to re-attend. I'm just so anxious. Would you like email updates of new search results? 2023 by the American Society of Neuroradiology | Print ISSN: 0195-6108 Online ISSN: 1936-959X. If we continue with pregnancy is there any future issue. Most children with mild, nonprogressive cases that do not involve brain damage or developmental anomalies will not have any long-term health effects. We never lose sight of the fact that your child is an individual, and we include your family at every stage of the treatment process. New points 1. Lok WY, Kong CW, Hui SYA, Shi MM, Choy KW, To WK, Leung TY. That work is planned but will include clinical and radiologic assessment when the children are 34 years of age, so it will not be available for some time. If the ventricles are only mildly enlarged (10 to 15 mm in size) and not getting bigger, and no brain damage or other abnormalities are found, there are usually no long-term consequences. Epub 2014 Mar 28. What causes ventriculomegaly in babies? Melchoirre et al9 reviewed 3 published studies that discussed symmetry of VM. Known as implantation bleeding, it happens when the fertilized egg attaches to the lining of the uterus about 10 to 14 days after conception. CSF is made in cavities in the brain called the lateral ventricles, and flows through the ventricles to surround the brain and spinal cord. 2019 Aug;54(2):164-171. doi: 10.1002/uog.20197. Schizencephaly is a rare malformation of the central nervous system. It is for educational purposes only and is not intended to replace the advice of your child's doctor or other health care provider. Ventriculomegaly is a condition in which the lateral ventricles (fluid-filled spaces in the brain) are larger than normal. Bethesda, MD 20894, Web Policies Ventriculomegaly is a condition in which the brain ventricles, or fluid-filled cavities, are enlarged due to build up of cerebrospinal fluid (CSF). Concerns? In the brain there are five fluid-filled holes called ventricles. These include the distressing experience of antenatal investigation and diagnosis, the acceptability of MR imaging itself, and the difficulties of re-establishing contact with patients based on medical records. Measurement of the trigones of the lateral ventricles is an important aspect of the routine anomaly scan.10,11 The importance of diagnosing fetuses with VM (trigone measurements 10 mm) has been reviewed extensively by Melchiorre et al,9 a work that contains many important meta-analyses. Two of the main factors that cause enlarged ventricles are: An injury or problem with brain development around the ventricles A blockage or imbalance in the ventricular system which prevents spinal fluid from moving or being absorbed normally Ventriculomegaly usually occurs spontaneously. In the 3032 weeks' group, 17/40 had isolated asymmetric VM and 11 of those were unilateral VM (6, mild; 3, moderate; and 2, severe). Our study showed a relatively high rate of unilateral VM, defined as 1 trigone 10 mm and the other 9 mm. The site is secure. after previously suffering two . We're ranked #1 in pediatric cancer, heart surgery, cardiology & more. I want a doctor to tell me treatment options. Shunt placement: In this process a small tube is implanted in the brain while the child is under anesthesia. 3 VM is defined as an axial atrial width of the lateral cerebral ventricles equal to or in excess of 10 mm, which is greater than 4 standard deviations (SD) above the mean of 7.6 0.6 mm. Epub 2014 Feb 26. Although karyotyping had been performed on some fetuses before the iuMR imaging, the results were not known at the time of referral. Firefox. National Library of Medicine Severe fetal ventriculomegaly (VM) is defined as an enlargement of the atria of the lateral cerebral ventricles (Vp) of greater than 15 mm. Follow UCSF Benioff Children's Hospitals: Follow UCSF Benioff Children's Hospital Oakland: A blockage that prevents CSF from circulating and being absorbed normally in the brain, A minor imbalance in CSF circulation and absorption. We set out to test the hypothesis that brain abnormalities other than VM would be obtained on a third-trimester iuMR imaging examination in at least 10% of cases. The primary purpose of this study, however, was to look for structural abnormalities of the fetal brain shown at 3032 weeks' gestational age but not on the 2024 weeks' study in fetuses originally referred with isolated VM. This produced categoric disagreements in 5/80 ventricles (3 between normal-sized ventricles and mild VM, and 2 between mild and moderate), with the categoric classification conflicting in 3/40 cases (2 normal-versus-mild, 1 mild-versus-moderate VM). Ventriculomegaly is when the fluid filled structures in the brain are too large. CA Federal government websites often end in .gov or .mil. We don't need people hounding us with questions and worry while we are in such a state ourselves. Ventriculomegaly may be mild or severe. In many fetuses, especially those with borderline ventriculomegaly, the condition resolves on its own, with no ill effects. J Obstet Gynaecol. That case was excluded from further analysis of ventricular size. We found out at 28 weeks that ventriculegaly had set in and began an amniocentesis. Sometimes a fetal MRI is also done to give more detailed images. It is widely accepted that severe VM is defined by a fetal trigone measurement of >15 mm, but there is disagreement about the classification of VM of 1015 mm. Boston Children's was the first hospital in the world to treat children with hydrocephalus by shunting. Outcomes for babies with ventriculomegaly depend on both the cause of the ventriculomegaly and whether it is progressive or not. The Wellcome Trust, Westfield Health, and The Health Foundation did not have any role in the design, in conducting this study, or in the preparation of this manuscript. Ventriculomegaly is the most common fetal brain abnormality, occurring in up to 1.5 in 1,000 pregnancies. When you are pregnant you will have an ultrasound. The brain has 4 ventricles - 2 at the top (on the left and right sides of the brain), one just below these two and one below the third one, near the top of the spine. When the infection occurs during pregnancy, the virus targets the fetal brain and retina, potentially causing ventriculomegaly, hydrocephalus, chorioretinitis, and neurodevelopmental abnormalities. Ventriculomegaly can be detected on prenatal tests or after the baby is born. Fetal Ventriculomegaly. Subsequent intervening antenatal sonography examinations may have been reassuring, signifying a good prognosis and discharge from specialist care, again implying that further examination was not required. No other issues were found at all so it is called mild isolated ventriculomegaly. Looks like youre visiting Benioff Children's Hospitals on Internet Explorer. Even so, the overall classification (based on the largest ventricle) disagreed in only 2/40 cases (both being normal-versus-mild VM). Mild Borderline Ventriculomegaly. The trigone measurements on iuMR imaging were performed independently by 2 researchers experienced in iuMR imaging (J.E.M. Ventriculomegaly is when the fluid filled structures in the brain are too large. In general, the outcome is worse when the ventricles are larger, the amniocentesis is abnormal, or there are other problems seen on the ultrasound. Our recent report showed a risk of other brain abnormalities of 6% in supposed isolated mild VM and of 14% in moderate VM.3. 1, 2 VM diagnosed in utero is found in 1%-2% of all pregnancies and is a common indication for more detailed fetal assessment. New comments cannot be posted and votes cannot be cast. It's usually due to a buildup of cerebrospinal fluid (CSF), the clear liquid surrounding the brain and spinal cord that cushions them from injury. NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. Sometimes the ultrasound will only show one of the lateral ventricles even though there are two (one on the right, and one on the left side). Mild ventriculomegaly is different from the more severe form of ventriculomegaly, hydrocephalus or "water on the brain". Six cases of schizencephaly were evaluated at one institution . This work was supported by Westfield Health for the salary of Mike Reeves, MD, as a Clinical Research Fellow, and by the Wellcome Trust, United Kingdom. . We also haven't discussed this with anybody at all. BACKGROUND AND PURPOSE: Although MR imaging of the fetal brain has been shown to provide additional diagnostic information, the optimal timing of the study and the value of repeat studies remain unclear. Ventriculomegaly is a condition in which the brain ventricles, or fluid-filled cavities, are enlarged due to build up of cerebrospinal fluid (CSF). 1-800-793-3887, 744 52nd Street, 3rd Floor Ventriculomegaly is a condition in which the ventricles appear larger than normal on a prenatal ultrasound. Fetal MRI is another way to safely look at your fetuss brain. Disclaimer. For more information on Fetal MRI please visit UCSF Baby Brain - Fetal MRI. Further research in the cases of unilateral VM and asymmetric VM supplemented by iuMR imaging is warranted. The women did not have any known or suspected contraindications to MR imaging and agreed to provide written consent after full explanation by 1 of the authors. Babies diagnosed with ventriculomegaly should be delivered in a hospital that is prepared to treat babies with complex birth defects so they can have access to a team of specialists and a neonatal intensive care unit (NICU). A and B, Axial single-shot fast spin-echo images show mild (A) and severe (B) VM. I just wanted to say Hello & let you know that I am going through a similar thing at the moment. When identified during pregnancy, a detailed evaluation of the brain by fetal MRI is recommended. FOIA Chromosome abnormality incidence in fetuses with cerebral ventriculomegaly. to assess reproducibility. What are the symptoms of ventriculomegaly in babies? I guess I'm hoping to find support in Internet strangers while we are in limbo. The prognosis and long-term outcomes greatly depend upon the etiology, the severity at diagnosis, progression, and associations. Pisapia JM, Sinha S, Zarnow DM, Johnson MP, Heuer GG. By itself, the condition is not necessarily a problem. It can happen on its own or be associated with infection, genetic problems or other birth defects, such as spina bifida or heart defects. My mom and dad will not be genuinely supportive (both are very much "me" people) and my FIL will make "jokes" about termination that we will find incredibly disturbing. We do have bloodwork in to rule out toxoplasmosis and CMV, another ultrasound appointment and a genetic counselling session booked. Why a fetus develops ventriculomegaly is not always clear, but four main events can cause the ventricles to expand: The outcome for a fetus with ventriculomegaly depends on several factors, including the size of the enlarged ventricles, whether the problem is getting worse, and whether there are other developmental or genetic abnormalities. Our Global Patient Services team is here to help international and out-of-area families every step of the way. R. RachelJCarter. Several different methods have been proposed to evaluate increased cerebrospinal fluid. These women may have reached a firm decision on the management of their pregnancy based on their second-trimester investigations and consultation, so they did not consider a repeat examination necessary. Discussion in 'Pregnancy - Third Trimester' started by Mommy2Kian, Aug 25, 2009. It's a condition that occurs in about 1 in 1,000 births. Fetal Medicine Unit Ventriculomegaly. Hydrocephalus can be treated soon after birth with a procedure that creates a pathway for extra fluid to drain out of the brain. Keep your blood sugar stable. MeSH You may feel your body making changes before you know you're pregnant or you may not notice any symptoms at all. We've got you covered.